资源类型

期刊论文 883

会议视频 55

会议专题 1

年份

2024 3

2023 89

2022 97

2021 98

2020 65

2019 57

2018 50

2017 46

2016 30

2015 44

2014 36

2013 24

2012 16

2011 29

2010 35

2009 41

2008 27

2007 38

2006 9

2005 10

展开 ︾

关键词

高速铁路 14

高质量发展 8

智能制造 6

运载系统 6

创新 5

关键技术 4

农业科学 4

城镇建设 4

技术体系 4

三峡工程 3

京沪高速铁路 3

发展 3

桥梁工程 3

高压 3

2021全球十大工程成就 2

2022全球工程前沿 2

中国高速铁路 2

交通 2

产业发展 2

展开 ︾

检索范围:

排序: 展示方式:

Crystal design of bismuth oxyiodide with highly exposed (110) facets on curved carbon nitride for the

《化学科学与工程前沿(英文)》 2022年 第16卷 第7期   页码 1125-1138 doi: 10.1007/s11705-021-2116-0

摘要: Crystalline materials with specific facet atomic arrangements and crystal facet structures exhibit unique functions according to their facet effects, quantum size effects and physical and chemical properties. In this study, a novel high-exposure (110) facet of bismuth oxyiodide (BiOI) was prepared (denoted as BiOI-110), and designed as nanosheets rich in oxygen vacancies by crystal facet design and regulation. Graphitic carbon nitride was designed as curved carbon nitride with dibromopyrazine, denoted as DCN, which contributed to a significant structural distortion in plane symmetry and improved the separation of charge carriers. Novel heterostructured BiOI-110/DCN nanosheets with a high-exposure (110) facet and abundant oxygen vacancies were successfully designed to enhance the photocatalytic degradation of organic pollutants. It was demonstrated that complete and tight contact between BiOI-110 and DCN was achieved by changing the size and crystal facet of BiOI. Oxytetracycline (OTC) and methyl blue dyes were used as targets for pollutant degradation, and 85.6% and 96.5% photocatalytic degradation efficiencies, respectively, were observed in the optimal proportion of 7% BiOI-110/DCN. The experimental results and electron spin resonance analysis showed that •O2 and h+ played a major role in the process of pollutant degradation. Additionally, high-resolution liquid chromatography-mass spectrography was used to identify the reaction intermediates of OTC, and the possible degradation pathway of this pollutant was proposed. Finally, the excellent reusability of BiOI-110/DCN nanomaterials was confirmed, providing a new approach for the removal of antibiotics that are difficult to biodegrade. Overall, crystal facet design has been proven to have broad prospects in improving the water environment.

关键词: high-exposure (110) facet     oxygen vacancy-rich     BiOI-110/DCN heterojunction     photocatalytic degradation     visible-light-response    

Possible role of power-to-vehicle and vehicle-to-grid as storages and flexible loads in the German 110

Erik BLASIUS

《能源前沿(英文)》 2017年 第11卷 第2期   页码 146-154 doi: 10.1007/s11708-017-0475-5

摘要: The sectoral coupling of road traffic (in form of E-Mobility) and electrical energy supply (known as power-to-vehicle (P2V), vehicle-to-grid (V2G) is discussed as one of the possible development concepts for the flexible system integration of renewable energy sources (RES) and the support of the objectives of the German energy transition (aka. Energiewende). It is obvious that E-mobility, which shall produce as few emissions as possible, should be based on the exclusive use of renewable energies. At the same time, the E-mobility can help to reduce the negative effects of the grid integration of RES to the distribution grids. However, this assumes that the electric vehicles are smart integrated to the grids where they charge, meaning that they must be able to communicate and be controllable. Because per se unplanned and uncontrollable charging processes are harmful for the grid operation, especially if they occur frequently and unexpected in similar time periods, the effects can hardly be controlled and can lead to serious technical problems in practical grid operation. This paper provides an insight into the current development of E-mobility in Germany. The insight will be matched with the German development of the RES. By the combination of both sectors, the possible role of the E-mobility for the distribution grid will be depicted, which can have positive and negative aspects.

关键词: P2V     V2G     grid integration     electric vehicles     distribution grid    

Sustaining health workforce recruitment and retention in township hospitals: a survey on 110 directors

null

《医学前沿(英文)》 2015年 第9卷 第2期   页码 239-250 doi: 10.1007/s11684-015-0392-0

摘要:

Township hospitals, the main provider of rural primary healthcare in China, are severely understaffed. International studies on factors influencing rural working are increasing; however, studies on factors affecting the recruitment and retention of health workers in Chinese township hospitals are limited. The current study aims to understand the motivation of health workers and arrive at a systematic framework of pluralistic factors that would help support health workers in terms of receiving posts and remaining in posts in township hospitals. A three-stage integrated quantitative and qualitative methodology was employed. First, a survey on 120 directors of township hospitals was conducted to learn the latest status of health workers in township hospitals and distinguish existing problems. Second, after sending these problems back to the directors, an open-ended pen-and-paper survey was conducted to ask the directors to identify the factors influencing the attraction and retention of health workers in township hospitals. Third, four focus groups were conducted to gauge the underlying reasons. Five problems from the questionnaire survey were recognized, and numbers of thematic factors were identified at the individual, professional, and treatment environment from the pen-and-paper survey and focus group. Similar to other studies, this framing of both non-financial and financial elements affected the attraction and retention of health workers in township hospitals, thereby filling the gap in a Chinese context. Although several factors had been recognized earlier, our findings further highlighted the importance of these factors. Meanwhile, the factors identified in this study were barely explored in literature. This paper identifies and develops multi-faceted factors to call for a bundled package of multidimensional incentives if decision-makers get interested. The evidence-based findings in our study can be used to provide China-specific policy recommendations on how to recruit and retain health workers in rural areas of China.

关键词: recruitment     retention     health workers     township hospitals     rural regions    

Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management

《环境科学与工程前沿(英文)》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1684-2

摘要:

● This study explored the long-term association by double robust additive models.

关键词: Air pollution     Cerebrovascular disease     Incidence     Long-term exposure     Doubly robust additive model    

Effective interventions on health effects of Chinese rural elderly under heat exposure

《环境科学与工程前沿(英文)》 2022年 第16卷 第5期 doi: 10.1007/s11783-022-1545-4

摘要:

● Education and subsidy were effective interventions during short-term heat exposure.

关键词: High temperature     Health effect     Comprehensive evaluation     Intervention     Rural elderly    

Untargeted metabolomic analysis of pregnant women exposure to perfluorooctanoic acid at different degrees

《环境科学与工程前沿(英文)》 2023年 第17卷 第3期 doi: 10.1007/s11783-023-1628-x

摘要:

● Metabolome can distinguish pregnant women exposure to PFOA at different degrees.

关键词: Perfluorooctanoic acid     Exposure     Pregnant women     Metabolomic     GSH     Microbiota metabolism    

Ultraviolet exposure enhanced silicon direct bonding

Guanglan LIAO, Xuekun ZHANG, Xiaohui LIN, Canghai MA, Lei NIE, Tielin SHI,

《机械工程前沿(英文)》 2010年 第5卷 第1期   页码 87-92 doi: 10.1007/s11465-009-0078-x

摘要: Ultraviolet (UV) exposure, as an additional technique following the traditional wet chemical activation processes, is applied to enhance hydrophilic silicon direct bonding. The effects of UV exposure on silicon wafers’ nano-topography and bonding strength are studied. It is found that the surface roughness of silicon wafers initially decreases and then increases with UV exposure time, and the bonding strength increases and then decreases accordingly. The correlations of annealing temperature and annealing time vs. bonding strength are experimentally explored. Results indicate that the bonding strength increases sharply then gently with increasing annealing temperature and annealing time using UV exposure. Besides, the reliability of silicon direct bonding with UV exposure enhancement after the high/low temperature cycle test, constant temperature and humidity test, vibration test and shock test is investigated. It follows from the results that the bonding strength of silicon wafer pairs with UV exposure decreases after the environmental tests, whereas the residual strength is still higher than that without UV exposure, and the variation trends of bonding strength vs. UV exposure time, annealing temperature and annealing time remain unchanged. Therefore, following the traditional wet chemical activation processes, appropriate UV exposure (about three minutes in this study) is effective and promising to enhance silicon direct bonding.

关键词: ultraviolet (UV) exposure     silicon direct bonding     bonding strength     reliability    

Paternal environmental exposure-induced spermatozoal small noncoding RNA alteration meditates the intergenerational

《医学前沿(英文)》 2022年 第16卷 第2期   页码 176-184 doi: 10.1007/s11684-021-0885-y

摘要: Studies of human and mammalian have revealed that environmental exposure can affect paternal health conditions as well as those of the offspring. However, studies that explore the mechanisms that meditate this transmission are rare. Recently, small noncoding RNAs (sncRNAs) in sperm have seemed crucial to this transmission due to their alteration in sperm in response to environmental exposure, and the methodology of microinjection of isolated total RNA or sncRNAs or synthetically identified sncRNAs gradually lifted the veil of sncRNA regulation during intergenerational inheritance along the male line. Hence, by reviewing relevant literature, this study intends to answer the following research concepts: (1) paternal environmental factors that can be passed on to offspring and are attributed to spermatozoal sncRNAs, (2) potential role of paternal spermatozoal sncRNAs during the intergenerational inheritance process, and (3) the potential mechanism by which spermatozoal sncRNAs meditate intergenerational inheritance. In summary, increased attention highlights the hidden wonder of spermatozoal sncRNAs during intergenerational inheritance. Therefore, in the future, more studies should focus on the origin of RNA alteration, the target of RNA regulation, and how sncRNA regulation during embryonic development can be sustained even in adult offspring.

关键词: small noncoding RNAs     epigenetic inheritance     paternal intergenerational inherence     extracellular vesicles    

An 84-month observational study of the changes in CD4 T-lymphocyte cell count of 110 HIV/AIDS patients

null

《医学前沿(英文)》 2014年 第8卷 第3期   页码 362-367 doi: 10.1007/s11684-014-0363-x

摘要:

This study aimed to evaluate the therapeutic effect of traditional Chinese medicine (TCM) by observing the changes in CD4 T-lymphocyte cell count of 110 cases with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) treated continuously with TCM for 84 months. Information of 110 HIV/AIDS patients from 19 provinces and cities treated with TCM from 2004 to 2013 was collected. Changes in the indexes of CD4 counts (≤200, 201–350, 351–500 and>500 cells/mm3) at five time points (0, 12, 36, 60 and 84 months) and different treatments [TCM and TCM plus antiretroviral therapy (ART)] were compared. Repeated measures test indicated no interaction between group and time (P>0.05). Degrees of increasing and decreasing CD4 count of the two groups at four different frames were statistically significant compared with the baseline. The CD4 count between the two groups was not statistically significant. For CD4 count of≤200 cells/mm3, the mean CD4 count changes were 21 and 28 cells/mm3 per year for the TCM group and TCM plus ART group, respectively. For CD4 count of 201–350 cells/mm3, the mean CD4 count changes were 6 and 25 cells/mm3 per year for the TCM group and TCM plus ART group, respectively. For CD4 count of 351–500 cells/mm3, the mean CD4 count changes were -13 and -7 cells/mm3 per year for the TCM group and TCM plus ART group, respectively. For CD4 count of>500 cells/mm3, the mean CD4 count changes were -34 and -17 cells/mm3 per year for the TCM group and TCM plus ART group, respectively. Long-term use of TCM could maintain or slow the pace of declining CD4 counts in patients with HIV/AIDS, and may achieve lasting effectiveness.

关键词: AIDS     HIV     CD4     traditional Chinese medicine     linear models    

Study of blood exposure-related mental health illness among clinical nurses

null

《医学前沿(英文)》 2017年 第11卷 第1期   页码 147-151 doi: 10.1007/s11684-016-0481-8

摘要:

Nurses are subjected to high amount of stress in the medical setting, and work-related stress often leads to mental problems. This study aims to investigate the mental health status of nurses exposed to blood through needlestick injuries. A total of 302 nurses working in the hospital of Guangdong, China, participated in this study. Out of the 302 nurses, 140 did not experience any needlestick injuries during the previous week, whereas 162 nurses experienced needlestick injuries. The General Health Questionnaire (GHQ)-28 Standardized Questionnaire, which uses physical, anxiety, social function, and depression subscales, was used in this study. No significant difference between nurses exposed to blood and nurses not exposed to blood was found in terms of gender, age, length of employment, and civil status (P>0.05). Results from the GHQ-28 Standardized Questionnaire showed that 75.9% (123/162) of nurses exposed to blood were suspected to suffer from mental disorders, whereas 40% (56/140) of nurses not exposed to blood were suspected to suffer from mental disorders. The mean mental health scores of nurses exposed to blood and those not exposed were 8.73±7.32 and 5.69±5.70, respectively. From these results, we can conclude that blood exposure from needlestick injuries leads to higher prevalence of depression, anxiety, and stress symptoms in nurses. This finding highlights the importance of providing efficient, adequate, and appropriate support services after nurses are exposed to blood from needlestick injuries.

关键词: blood exposure     needlestick injuries     mental health     nurses    

Effects of hemin and thermal stress exposure on JWA expression

ZHAO Ming, CHEN Rui, LI Aiping, ZHOU Jianwei

《医学前沿(英文)》 2007年 第1卷 第1期   页码 104-108 doi: 10.1007/s11684-007-0020-8

摘要: To investigate the expression of JWA after hemin and (or) thermal stress exposure, we treated K562 (chronic myelogenous leukemia cells) cells with different doses of hemin and thermal stress using different exposure times. The expression of JWA protein was determined by Western blot analysis. Reverse transcription-polymerase chain reaction was carried out to determine JWA mRNA expression. JWA promoter transcription activity analysis was performed by chloramphenicol acetyl transferase-enzyme linked immunosorbent assay (CAT-ELISA). The expression of JWA protein was significantly increased by up to (3.23±0.57) folds compared to the control in K562 cells after hemin treatment (50 µM for one week), and a similar pattern was observed in the cells after treatment with thermal stress (42 °C) for 2 hours [increased by (8.00±1.73) folds]. The expression of JWA mRNA was also significantly elevated by up to (1.37±0.06) folds in K562 cells treated with hemin (30 µM for 48 hours), and a similar regulatory pattern [increased by (1.87±0.13) folds] was observed with thermal stress exposure (42 °C) for 30 minutes. However, a combined antagonistic effect was observed in the treatment of K562 cells with hemin (30 µM, 48 h) followed by thermal stress (42 °C, 30 min). CAT-ELISA further confirmed that either hemin or thermal stress treatment could up-regulate JWA transcription activity, however, the effects could be counteracted partly by treatment with a combination of both. Hemin and thermal stress might regulate JWA expression via distinct intracellular signal transduction pathways.

Understanding of Support Effects in Pd-Catalyzed Semi-Hydrogenation of Acetylene” [Engineering 7 (2021) 103–110 Corrigendum

Yueqiang Cao, Xiaohu Ge, Yurou Li, Rui Si, Zhijun Sui, Jinghong Zhou, Xuezhi Duan, Xinggui Zhou

《工程(英文)》 2021年 第7卷 第5期   页码 701-701 doi: 10.1016/j.eng.2021.04.001

Occupational risk of exposure to methicillin-resistant (MRSA) and the quality of infection hygiene in

《环境科学与工程前沿(英文)》 2021年 第15卷 第3期 doi: 10.1007/s11783-020-1333-y

摘要:

• Staff members were not colonised with MRSA.

关键词: Antibiotic resistance     Airborne MRSA     Bioaerosols     Healthcare-associated infections     Healthcare worker     Occupational health    

Universal influenza virus vaccines: what can we learn from the human immune response following exposure

null

《医学前沿(英文)》 2017年 第11卷 第4期   页码 471-479 doi: 10.1007/s11684-017-0602-z

摘要:

Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutinin stalk domain are in development. Typically, these vaccines induce responses that target group 1 or group 2 hemagglutinins with little to no cross-group reactivity and protection. Similarly, the majority of human anti-stalk monoclonal antibodies that have been isolated are directed against group 1 or group 2 hemagglutinins with very few that bind to hemagglutinins of both groups. Here we review what is known about the human humoral immune response to vaccination and infection with H7 subtype influenza viruses on a polyclonal and monoclonal level. It seems that unlike vaccination with H5 hemagglutinin, which induces antibody responses mostly restricted to the group 1 stalk domain, H7 exposure induces both group 2 and cross-group antibody responses. A better understanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza virus vaccine candidates.

关键词: universal influenza virus vaccine     hemagglutinin stalk     H7N9    

Response of bacterial communities to short-term pyrene exposure in red soil

Jingjing PENG, Hong LI, Jianqiang SU, Qiufang ZHANG, Junpeng RUI, Chao CAI

《环境科学与工程前沿(英文)》 2013年 第7卷 第4期   页码 559-567 doi: 10.1007/s11783-013-0501-8

摘要: Pyrene, a representative polycyclic aromatic hydrocarbon (PAH) compound produced mainly from incomplete combustion of fossil fuels, is hazardous to ecosystem health. However, long-term exposure studies did not detect any significant effects of pyrene on soil microorganism. In this study, short-term microcosm experiments were conducted to identify the immediate effect of pyrene on soil bacterial communities. A freshly-collected pristine red soil was spiked with pyrene at 0, 10, 100, 200, and 500 mg·kg and incubated for one day and seven days. The bacterial communities in the incubated soils were analyzed using 16S rRNA sequencing and terminal restriction fragment length polymorphism (T-RFLP) methods. The results revealed high bacterial diversity in both unspiked and pyrene-spiked soils. Only at the highest pyrene-spiking rate of 500 mg·kg , two minor bacteria groups of the identified 14 most abundant bacteria groups were completely suppressed. Short-term exposure to pyrene resulted in dominance of Proteobacteria in soil, followed by Acidobacteria, Firmutes, and Bacteroidetes. Our findings showed that bacterial community structure did respond to the presence of pyrene but recovered rapidly from the perturbation. The intensity of impact and the rate of recovery showed some pyrene dosage-dependent trends. Our results revealed that different levels of pyrene may affect the bacterial community structure by suppressing or selecting certain groups of bacteria. It was also found that the bacterial community was most susceptible to pyrene within one day of the chemical addition.

关键词: pyrene     bacterial communities     terminal restriction fragment length polymorphism     short-term exposure     rank-abundance plots    

标题 作者 时间 类型 操作

Crystal design of bismuth oxyiodide with highly exposed (110) facets on curved carbon nitride for the

期刊论文

Possible role of power-to-vehicle and vehicle-to-grid as storages and flexible loads in the German 110

Erik BLASIUS

期刊论文

Sustaining health workforce recruitment and retention in township hospitals: a survey on 110 directors

null

期刊论文

Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management

期刊论文

Effective interventions on health effects of Chinese rural elderly under heat exposure

期刊论文

Untargeted metabolomic analysis of pregnant women exposure to perfluorooctanoic acid at different degrees

期刊论文

Ultraviolet exposure enhanced silicon direct bonding

Guanglan LIAO, Xuekun ZHANG, Xiaohui LIN, Canghai MA, Lei NIE, Tielin SHI,

期刊论文

Paternal environmental exposure-induced spermatozoal small noncoding RNA alteration meditates the intergenerational

期刊论文

An 84-month observational study of the changes in CD4 T-lymphocyte cell count of 110 HIV/AIDS patients

null

期刊论文

Study of blood exposure-related mental health illness among clinical nurses

null

期刊论文

Effects of hemin and thermal stress exposure on JWA expression

ZHAO Ming, CHEN Rui, LI Aiping, ZHOU Jianwei

期刊论文

Understanding of Support Effects in Pd-Catalyzed Semi-Hydrogenation of Acetylene” [Engineering 7 (2021) 103–110

Yueqiang Cao, Xiaohu Ge, Yurou Li, Rui Si, Zhijun Sui, Jinghong Zhou, Xuezhi Duan, Xinggui Zhou

期刊论文

Occupational risk of exposure to methicillin-resistant (MRSA) and the quality of infection hygiene in

期刊论文

Universal influenza virus vaccines: what can we learn from the human immune response following exposure

null

期刊论文

Response of bacterial communities to short-term pyrene exposure in red soil

Jingjing PENG, Hong LI, Jianqiang SU, Qiufang ZHANG, Junpeng RUI, Chao CAI

期刊论文